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해외여행자의 Atovaquone-proguanil 순응도

Compliance with Atovaquone-Proguanil against Malaria of Korean Travelers Abroad

감염과화학요법 2008년 40권 5호 p.255 ~ 258
권낙현, 신형식, 강효성, 김재윤, 박태수, 노혜진, 황래석, 김성훈, 방지환,
소속 상세정보
권낙현 ( Kwon Nak-Hyun ) - 국립의료원 내과
신형식 ( Shin Hyoung-Shik ) - 국립의료원 내과
강효성 ( Kang Hyo-Sung ) - 국립의료원 내과
김재윤 ( Kim Jae-Youn ) - 국립의료원 소아과
박태수 ( Park Tae-Soo ) - 국립의료원 소아과
노혜진 ( Noh Hye-Jin ) - 국립의료원 내과
황래석 ( Hwang Lae-Seok ) - 국립의료원 내과
김성훈 ( Kim Sung-Hoon ) - 국립의료원 내과
방지환 ( Bang Ji-Hwan ) - 국립의료원 내과

Abstract


Background : Recently, many Korean people travel abroad where malaria is prevalent. However, in Korea, relatively little is known about compliance of chemoprophylaxis against malaria. This study was performed to determine the factors influencing compliance of chemoprophylaxis against malaria in Korean travelers.

Materials and Methods : Face to face interview, telephone interview and e-mail correspondence were performed to 241 people who were prescribed with atovaquone-proguanil at the international travelers’ clinic of National Medical Center between February 2007 and October 2007.

Results : Total of 55 people out of 235 reported one or more events of adverse reactions after chemoprophylaxis (total 76 events). However, in 38 adverse events the link between chemoprophylaxis and adverse events were very weak. Compliance of malaria chemoprophylaxis with atovaquone-proguanil was 53.9% in the study group. The predictive factors for non-compliance were package tour, travel of business affair and young age group.

Conclusions : Compliance of malaria chemoprophylaxis in Korea travelers was low compared with Dutch and French studies. More efforts to increase compliance are needed, especially in travelers on package tour, business travel and people under age 40.

키워드

Travel;Malaria;Chemoprophylaxis;Compliance;Atovaquone-proguanil

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등재저널 정보

KCI
KoreaMed
KAMS