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스테로이드를 투여 받는 환자에서 발생한 Nocardia farcinica 뇌 농양 1예

A Case of Nocardia farcinica Brain Abscess in the Patient Receiving Steroid Treatment

감염과화학요법 2008년 40권 5호 p.301 ~ 304
심성훈, 김남중, 오명돈, 최강원, 김의종, 김충종, 박혜인조, 전재현,
소속 상세정보
심성훈 ( Sim Sung-Hoon ) - 서울대학교 의과대학 내과학교실
김남중 ( Kim Nam-Joong ) - 서울대학교 의과대학 내과학교실
오명돈 ( Oh Myoung-Don ) - 서울대학교 의과대학 내과학교실
최강원 ( Choe Kang-Won ) - 서울대학교 의과대학 내과학교실
김의종 ( Kim Eui-Chong ) - 서울대학교 의과대학 진단검사의학교실
김충종 ( Kim Chung-Jong ) - 서울대학교 의과대학 내과학교실
박혜인조 ( Park Hayne-Cho ) - 서울대학교 의과대학 내과학교실
전재현 ( Jeon Jae-Hyun ) - 서울대학교 의과대학 내과학교실

Abstract


Nocardiosis occurs mostly in the immunocompromised patients. N. farcinica is known to have resistance to some antibiotics and significant increase in morbidity and mortality in patients requiring long-term treatment. Nocardia farcinica infection, especially brain abscess, has not been reported in Korea. Here, we report a case of N. farcinica brain abscess in a patient receiving steroid treatment. The patient was a 64 year-old male with gouty arthritis. He received steroid for more than two months, because of allopurinol-hypersensitivity syndrome with skin rash. After three months of steroid therapy, he visited other hospital with mild fever and left thigh pain and was diagnosed of intramuscular abscess due to gram positive bacilli. One month later, he visited our hospital with right side weakness and was diagnosed as brain abscess. The causative organism turned out to be N. farcinica, which was confirmed by means of 16S rRNA sequencing. Antibiotics were selected by E-test results and treatment was successful.

키워드

Nocardia farcinica;Brain abscess;Steroids;Immunocompromised host

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등재저널 정보

KCI
KoreaMed
KAMS