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폐경 후 여성의 치주질환 심도에 따른 골다공증 소견

Osteoporotic Condition in Postmenopausal Patients with Periodontitis

구강과학- 전남대학교 2002년 14권 4호 p.336 ~ 344
김강문, 황현식, 정현주,
소속 상세정보
김강문 (  ) - 전남대학교 치의학연구소, 치과대학
황현식 (  ) - 전남대학교 치의학연구소, 치과대학
정현주 (  ) - 전남대학교 치의학연구소, 치과대학

Abstract


The purpose of this study was to evaluate the relationship between the osteoporotic condition and periodontal condition in postmenopausal women with periodontitis. Forty three female postmenopausal patients with no systemic disease were grouped into 3 groups by their periodontal conditions;12 mild periodontitis. 11 moderate periodontitis, 20 advanced periodontitis. From each patient, age of menopause was taken, alkaline phosphatase(ALP) and osteocalcin (OC) in blood and deoxypyridinoline (DPD) in urine were measured. Bone mineral density (BMD) of lumbar spine (L2- L4) was measured by dual energy X-ray absorptiometry. Periodontal and osteoporotic parameters were compared among the groups and correlation coefficient between them was evaluated.
1. The blood ALP and OC levels were similar among the groups with different periodontal condition. whereas the urine DPD level and BMD were significantly lower in advanced periodontitis group than the other groups (p<0.01)
2. Probing depth was negatively related with BMD (r=-0.5, p<0.01) and positively related with patient age and the duration of menopause (r= 0.32 and 0.35 respectively, p<0.05)
3. Clinical attachment loss was negatively related with BMD (r=-0.66, p<0.01), and positively related with urine DPD (r= 0.37. p<0.05).
These results showed that postmenopausal women with advanced periodontitis had significantly decreased bone mineral density and suggested that decreased bone mineral density in postmenopausal women could be associated with periodontal tissue breakdown.

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