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Fluconazole에 저항성을 보이는 구강 캔디다증 환자에서 Itraconazole의 활용에 관한 보고

Itraconazole Use in Patients with Oral Candidiasis Refractory to Fluconazole: Two Cases

대한노년치의학회지 2018년 14권 1호 p.9 ~ 16
강민구, 고홍섭,
소속 상세정보
강민구 ( Kang Min-Goo ) - Seoul National University School of Dentistry Department of Oral Medicine and Oral Diagnosis
고홍섭 ( Kho Hong-Seop ) - Seoul National University School of Dentistry Department of Oral Medicine and Oral Diagnosis

Abstract


Oral candidiasis caused by opportunistic infection of the genus Candida is one of common geriatric oral mucosal diseases. Antifungal medications such as nystatin or fluconazole are widely used for treating oral candidiasis, but there are some patients who are refractory to these commonly used antifungal medications. In this case report, we present two patients who turned out refractory oral candidiasis to fluconazole and showed significant reduction of clinical signs and symptoms following itraconazole treatment. Itraconazole could be one of treatment options for the treatment of oral candidiasis not responding to fluconazole.

키워드

Fluconazole; Itraconazole; Oral candidiasis

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