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Are Platelet Indices such as Platelet Volume, Platelet Distribution Width, and Plateletcrit Associated with Peyronie Disease?

The World Journal of Men′s Health 2020년 38권 3호 p.353 ~ 358
Cakir Suleyman Sami, Ozbir Sait, Atalay Hasan Anil, Culha Mehmet Gokhan, Can Osman, Canat Halil Lutfi,
소속 상세정보
 ( Cakir Suleyman Sami ) - Okmeydani Training and Research Hospital Department of Urology
 ( Ozbir Sait ) - Okmeydani Training and Research Hospital Department of Urology
 ( Atalay Hasan Anil ) - Okmeydani Training and Research Hospital Department of Urology
 ( Culha Mehmet Gokhan ) - Okmeydani Training and Research Hospital Department of Urology
 ( Can Osman ) - Okmeydani Training and Research Hospital Department of Urology
 ( Canat Halil Lutfi ) - Okmeydani Training and Research Hospital Department of Urology

Abstract


Purpose: Peyronie disease (PD) occurs as a result of recurrent microvascular injuries or trauma of the tunica albuginea, although its precise etiology is unknown. Mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), which are parameters indicative of platelet activity, are considered to be functional markers of platelets involved in the pathophysiology of related inflammatory and vascular diseases. In this study, we aimed to examine the relationship between PD and platelet indices.

Materials and Methods: We evaluated participants who presented to the andrology department of our institution between December 2015 and May 2018. Ninety-two men with PD and 80 healthy volunteers were included in this study. Participants who had received medical treatment affecting platelets or had any hematologic or systemic diseases were excluded from the study.

Results: The mean age of men with PD was 53.8±10.2 years, and the mean age of the control group was 52.2±8.0 years (p=0.465). There were no significant differences in the mean IIEF-5 scores, platelet count, MPV, PDW, or PCT between the patients with and without PD (p<0.05).

Conclusions: No correlations were found between PD and platelet indices. Large-scale prospective cross-sectional studies are needed to elucidate the etiopathogenesis of PD.

키워드

Mean platelet volume; Peyronie disease; Platelet distribution width; Plateletcrit

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