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Fecal Microbiota Transplantation: Is It Safe?

Clinical Endoscopy 2021년 54권 2호 p.157 ~ 160
박선영, 서검석,
소속 상세정보
박선영 ( Park Seon-Young ) - Chonnam National University Medical School Department of Internal Medicine
서검석 ( Seo Geom-Seog ) - Wonkwang University College of Medicine Department of Internal Medicine

Abstract


Fecal microbiota transplantation (FMT) is an accepted procedure for the management of recurrent Clostridioides difficile infections. FMT is generally considered safe and well-tolerated - even in high-risk patients. Most short-term risks are mild and known to be associated with delivery methods. Long-term side effects have not been established, and no signs of harm have been found to date. However, causality for several microbiome-associated diseases has to be established. Even though FMT is generally considered safe with strict donor screening, serious adverse events have been recently associated with the FMT product from the stool bank, where screening for multi-drug resistant organisms is not included in protocols. Here, we discuss the adverse events associated with FMT and safety issues.

키워드

Adverse events; Fecal microbiota transplantation; Safety

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