잠시만 기다려 주세요. 로딩중입니다.

Effectiveness of preoperative ultrasound-guided charcoal tattooing for localization of metastatic melanoma

Ultrasonography 2020년 39권 4호 p.376 ~ 383
이지현, 김현수, 윤영철, 김민제, 차민재, 김중한,
소속 상세정보
이지현 ( Lee Ji-Hyun ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Radiology
김현수 ( Kim Hyun-Su ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Radiology
윤영철 ( Yoon Young-Cheol ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Radiology
김민제 ( Kim Min-Je ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Radiology
차민재 ( Cha Min-Jae ) - Chung-Ang University College of Medicine Chung-Ang University Hospital Department of Radiology
김중한 ( Kim Jung-Han ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Surgery

Abstract


Purpose: Excision of metastatic lesions is an important treatment strategy in patients with malignant melanoma, both at the initial diagnosis and upon recurrence. Since nonpalpable lesions cannot be easily visualized in the surgical field, we evaluated the effectiveness of ultrasound (US)-guided tattooing using a charcoal suspension for the localization of nonpalpable metastatic lesions of malignant melanoma.

Methods: Between November 2009 and June 2019, we retrospectively reviewed 65 nonpalpable lesions in 29 patients with malignant melanoma who underwent preoperative US-guided tattooing using a charcoal suspension for histologically confirmed or suspected metastases. The characteristics of the tattooed lesions were analyzed. The effectiveness of the procedure was evaluated based on the detection rate in the surgical field and the presence or absence of residua on postoperative follow-up US. Procedure-related complications were also analyzed.

Results: Of 65 lesions, 33 (50.8%) were histologically confirmed as metastases before the tattooing procedure, while the other 32 were suspected of being metastases based on imaging studies. The mean lesion size was 9.8 mm (range, 1.3 to 24.4 mm). The final pathology revealed metastases in 59 lesions (90.8%), including lymph node (n=51), muscle (n=5), and in-transit (n=3) metastases. Sixty-one lesions (93.8%) were successfully detected intraoperatively and removed without residua on follow-up US. Four residual lesions were removed after repeated localization (n=2) or by intraoperative US (n=2). No relevant complications were noted.

Conclusion: Preoperative US-guided tattooing localization can safely and effectively delineate nonpalpable metastatic melanoma lesions to aid in successful surgical excision.

키워드

Ultrasonography; Interventional ultrasonography; Melanoma; Neoplasm metastasis; Tattooing

원문 및 링크아웃 정보

등재저널 정보

KCI
KoreaMed