잠시만 기다려 주세요. 로딩중입니다.

Associations of depression and anxiety with cardiovascular risk among people living with HIV/AIDS in Korea

Epidemiology and Health 2021년 43권 1호 p.2 ~ 2
박경실, 황선영, 최보율, 김준, 김상일, 김우주, Kang Chun,
소속 상세정보
박경실 ( Park Kyong-Sil ) - Cheju Halla University School of Nursing
황선영 ( Hwang Seon-Young ) - Hanyang University School of Nursing
최보율 ( Choi Bo-Youl ) - Hanyang University Institute for Health and Society
김준 ( Kim June ) - Yonsei University College of Medicine Department of Internal Medicine
김상일 ( Kim Sang-Il ) - Catholic University College of Medicine Seoul St. Mary’s Hospital Department of Internal Medicine
김우주 ( Kim Woo-Joo ) - Korea University College of Medicine Department of Internal Medicine
 ( Kang Chun ) - Korea National Institute of Health Division of AIDS

Abstract


OBJECTIVES: As HIV/AIDS is becoming a chronic disease, the risk of developing cardiovascular disease (CVD) among people living with HIV/AIDS is rising. Anxiety and depression, which are common among people living with HIV/AIDS, have been linked with CVD. This study investigated the risk of CVD in people living with HIV/AIDS and explored the effects of depression and anxiety on CVD risk.

METHODS: Data were collected for 457 people enrolled in the Korea Cohort HIV/AIDS study after 2010. Framingham risk scores were calculated to quantify the 10-year risk of developing CVD. Depression and anxiety variables were re-coded as a single combined variable. Multivariable logistic regression analysis was performed, adjusting for age, body mass index, low-density lipoprotein (LDL) cholesterol, triglycerides (TG), duration of human immunodeficiency virus (HIV) positivity after entry into the cohort, and depression/anxiety.

RESULTS: Participants with both depression and anxiety were 2.28 times more likely than those with neither depression nor anxiety to have moderate/high-risk CVD risk. The 10-year risk of developing CVD was affected by LDL cholesterol, TG, age, and duration of HIV infection. LDL cholesterol and TG levels change according to the duration of HIV infection, and metabolic disorders affect the risk of CVD. Thus, a longer duration of HIV infection is associated with a higher risk of developing CVD.

CONCLUSIONS: Screenings for depression and anxiety need to be provided regularly to assess the severity of those symptoms. To help decrease their risk of developing CVD, people living with HIV/AIDS should be offered behavioral modification interventions aimed at developing healthy lifestyle habits.

키워드

Acquired immunodeficiency syndrome; Anxiety; Cardiovascular disease; Depressive disorder; Human immunodeficiency virus

원문 및 링크아웃 정보

등재저널 정보