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Cohort profile: the Ewha Birth and Growth Study

Epidemiology and Health 2021년 43권 1호 p.16 ~ 16
이혜아, 박보현, 민정원, 최은정, 김의정, 박현진, 박은애, 조수진, 김혜순, 이화영, 김영주, 홍영순, 김의중, 하은희, 박혜숙,
소속 상세정보
이혜아 ( Lee Hye-Ah ) - Ewha Womans University Mokdong Hospital Clinical Trial Center
박보현 ( Park Bo-Hyun ) - National Cancer Center National Cancer Control Institute
민정원 ( Min Jung-won ) - Children’s Hospital of Philadelphia Department of Biomedical and Health Informatics
최은정 ( Choi Eun-Jeong ) - Ewha Womans University School of Medicine Department of Preventive Medicine
김의정 ( Kim Ui-Jeong ) - Ewha Womans University School of Medicine Department of Preventive Medicine
박현진 ( Park Hyun-Jin ) - Ewha Womans University School of Medicine Department of Preventive Medicine
박은애 ( Park Eun-Ae ) - Ewha Womans University School of Medicine Department of Pediatrics
조수진 ( Cho Su-Jin ) - Ewha Womans University School of Medicine Department of Pediatrics
김혜순 ( Kim Hae-Soon ) - Ewha Womans University School of Medicine Department of Pediatrics
이화영 ( Lee Hwa-Young ) - Ewha Womans University School of Medicine Department of Anatomy
김영주 ( Kim Young-Ju ) - Ewha Womans University School of Medicine Department of Obstetrics and Gynecology
홍영순 ( Hong Young-Sun ) - Ewha Womans University School of Medicine Department of Internal Medicine
김의중 ( Kim Eui-Jung ) - Ewha Womans University School of Medicine Department of Psychiatry
하은희 ( Ha Eun-Hee ) - Ewha Womans University School of Medicine Department of Occupational and Environmental Medicine
박혜숙 ( Park Hye-Sook ) - Ewha Womans University School of Medicine Department of Preventive Medicine

Abstract


With the introduction of life-course epidemiology, researchers realized the importance of identifying risk factors in early life to prevent chronic diseases. This led to the establishment of the Ewha Birth and Growth Study in 2001; the study is a prospective birth cohort designed to provide evidence of early life risk factors for a child’s growth and health. Participants were recruited from those who visited Ewha Womans University Mokdong Hospital (a tertiary hospital in southwest Seoul, Korea) for prenatal care at 24-28 weeks of gestation. In total, 891 mothers enrolled in this study between 2001 and 2006 and their offspring (n=940) were followed-up. Regular check-up examinations of offspring were conducted at 3 years, 5 years, and 7 years of age and every year thereafter. To consider age-related health issues, extensive data were collected using questionnaires and measurements. In 2021, the study subjects will reach 19 years of age, and we are planning a check-up examination for early adulthood. About 20 years have passed since the cohort data were collected, and we have published results on childhood health outcomes associated with prenatal and birth characteristics, genetic and epigenetic characteristics related to childhood metabolism, the effects of exposure to endocrine disruptors, and dietary patterns in childhood. Recently, we started reporting on topics related to adolescent health. The findings will facilitate identification of early life risk factors for chronic diseases and the development of interventions for diseases later in life.

키워드

Cohort studies; Child health; Cardiometabolic risk factors; Metabolic syndrome

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