잠시만 기다려 주세요. 로딩중입니다.

Seasonal Changes in Vitamin D Levels of Healthy Children in Mid-Latitude, Asian Urban Area

원종우, 정성관, 정인아, 이윤,
소속 상세정보
원종우 ( Won Jong-Woo ) - Korea University Medical Center Department of Pediatrics
정성관 ( Jung Seong-Kwan ) - Woorisoa Children’s Hospital Department of Pediatrics
정인아 ( Jung In-Ah ) - Woorisoa Children’s Hospital Department of Pediatrics
이윤 ( Lee Yoon ) - Korea University Medical Center Department of Pediatrics

Abstract


Purpose: This study aimed to investigate the seasonal changes in vitamin D levels in a healthy pediatric population living in mid-latitude East Asian urban areas.

Methods: A pediatric population was selected from single secondary hospital visitors. Clinical data and serum vitamin D levels were collected retrospectively. Statistical analyses were performed based on the month of the blood sampling date, subject age, and vitamin D supplementation history. The data were categorized into three subgroups based on serum vitamin D levels?adequate (≥30 ng/mL), insufficient (20?29 ng/mL), and deficient (<20 ng/mL).

Results: Of the 481 patients, 172 had vitamin D supplementation history. More than 70% of the total study population had inadequate vitamin D levels (<30 ng/mL). The non-supplemented group and the supplemented group showed significantly uneven monthly distribution of the adequate, insufficient, and deficient subgroups. Only the non-supplemented group showed significantly different average vitamin D levels in the summer months compared to the winter months. In the non-supplemented group, vitamin D levels were the lowest in March, the highest in August and September. Significant relevance was noted between vitamin D supplementation status and vitamin D serum level in February and March. There was no significant difference between different age groups in terms of the distribution of vitamin D levels.

Conclusion: Currently-widespread vitamin D replacement methods seem to have some effect on increasing the overall serum vitamin D levels, specifically during late winter when natural serum vitamin D levels plunge. However, they are unable to fully compensate the seasonal fluctuation.

키워드

Vitamin D; Calcitriol; Vitamin D deficiency; Seasons; Infant; Child

원문 및 링크아웃 정보

등재저널 정보