잠시만 기다려 주세요. 로딩중입니다.

Conventional Chemoembolization for Hepatocellular Carcinoma: Role of Cone-Beam Computed Tomography Guidance

대한간암학회지 2019년 19권 1호 p.19 ~ 29
이인준, 정진욱,
소속 상세정보
이인준 ( Lee In-Joon ) - National Cancer Center Department of Radiology
정진욱 ( Chung Jin-Wook ) - Seoul National University College of Medicine Seoul National University Hospital Department of Radiology

Abstract


Conventional chemoembolization using Lipiodol-based regimens was introduced in the 1980s, and it is currently recommended as the primary treatment modality for patients with unresectable, intermediate, or locally advanced hepatocellular carcinoma (HCC) by the international guidelines. For better therapeutic efficacy and safety, chemoembolization should be performed as selectively as possible through tumor-feeding arteries, based on the detection of arterial supply to the HCC. With the technical advancement of flat-panel detector, cone-beam computed tomography (CBCT) is mounted on the C-arm of the angiographic machine. CBCT facilitates the detection of small occult HCCs and fine tumor-feeding arteries, recognition of extrahepatic collateral supply, navigation of a microcatheter to the target feeding arteries, prevention of non-target embolization, and intraprocedural assessment of the completeness of treatment with chemoembolization. These functions performed by CBCT ultimately improve the safety and efficacy of chemoembolization and may contribute to improving the prognosis of the patient with HCC.

키워드

Hepatocellular carcinoma; Therapeutics; Cone-beam computed tomography

원문 및 링크아웃 정보

 

등재저널 정보