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Hepatocellular Carcinoma with Segmental Portal Vein Invasion Exhibiting a Complete Response after Transarterial Radioembolization

대한간암학회지 2019년 19권 2호 p.159 ~ 164
윤준식, 유수종, 이윤빈, 조은주, 이정훈, 김윤준, 윤정환,
소속 상세정보
윤준식 ( Yoon Jun-Sik ) - Seoul National University College of Veterinary Medicine Department of Internal Medicine
유수종 ( Yu Su-Jong ) - Seoul National University College of Medicine Department of Internal Medicine
이윤빈 ( Lee Yun-Bin ) - Seoul National University College of Medicine Department of Internal Medicine
조은주 ( Cho Eun-Ju ) - Seoul National University College of Medicine Department of Internal Medicine
이정훈 ( Lee Jeong-Hoon ) - Seoul National University Hospital Department of Internal Medicine
김윤준 ( Kim Yoon-Jun ) - Seoul National University College of Medicine Department of Internal Medicine
윤정환 ( Yoon Jung-Hwan ) - Seoul National University College of Medicine Department of Internal Medicine

Abstract


The treatment options available for patients with hepatocellular carcinoma (HCC) with portal vein invasion (PVI) include sorafenib, transarterial radioembolization (TARE), radiation therapy (RT), transarterial chemoembolization with RT, and proton beam irradiation. Herein, we present a case of HCC with segmental PVI that was managed via TARE. The patient had a 4 cm HCC that invaded the segment VIII portal vein branch without extrahepatic spread. Liver function was Child-Pugh grade A, and performance status was good. TARE was performed without any adverse events, and a radiological complete response (CR) was achieved. Thereafter, the patient was followed-up every 3-6 months without any further treatment, and the CR was maintained for >3 years. Therefore, TARE may be a useful alternative therapeutic option for patients with HCC exhibiting segmental PVI.

키워드

Hepatocellular carcinoma; Venous thrombosis; Radiotherapy; Therapeutic embolization; Yttrium-90

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