잠시만 기다려 주세요. 로딩중입니다.

Renal intravascular large B cell lymphoma: the first case report in Korea and a review of the literature

Journal of Pathology and Translational Medicine 2020년 54권 5호 p.426 ~ 431
김문식, 정해림, 양우익, 정현주,
소속 상세정보
김문식 ( Kim Moon-Sik ) - Yonsei University College of Medicine Department of Pathology
정해림 ( Chung Hae-Rim ) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
양우익 ( Yang Woo-Ick ) - Yonsei University College of Medicine Department of Pathology
정현주 ( Jeong Hyeon-Joo ) - Yonsei University College of Medicine Department of Pathology

Abstract


Herein, we describe the first case of renal intravascular large B cell lymphoma in Korea occurring in a 66-year-old female. She presented with mild fever and dyspnea. On physical and laboratory evaluations, hemophagocytic lymphohistiocytosis was suspected, but the bone marrow biopsy results were unremarkable. During the work-up, massive proteinuria developed, which led to a renal biopsy. The renal architecture was relatively well-preserved, but the glomeruli were hypercellular with the infiltration of atypical, large lymphoid cells with increased nucleus-cytoplasm ratio and clumped chromatin. Similar cells were also present in the peritubular capillaries. The tumor cells exhibited membranous staining for CD20 and CD79a. After the diagnosis of intravascular large B cell lymphoma, the patient received rituximab-based chemotherapy under close follow-up.

키워드

Intravascular large B cell lymphoma; Kidney glomerulus; Peritubular capillary

원문 및 링크아웃 정보

등재저널 정보