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한국인을 대상으로 한 혈중 Vitamin A, E 농도와 당뇨병 유병률의 상관관계: 2016?2018년 국민건강영양조사 자료를 이용하여

Association between Vitamin A, E and Type 2 Diabetes Mellitus in Korea: Korean National Health and Nutrition Examination Survey 2016?2018

가정의학 2021년 11권 2호 p.135 ~ 141
김경표, 최준호, 박성배,
소속 상세정보
김경표 ( Kim Kyung-Pyo ) - Yonsei University College of Medicine Severance Hospital Department of Family Medicine
최준호 ( Choi Jun-Ho ) - National Health Insurance Service Ilsan Hospital Department of Family Medicine
박성배 ( Pak Serng-Bai ) - National Health Insurance Service Ilsan Hospital Department of Family Medicine

Abstract


Background: This study aimed to analyze the association of vitamins A and E with type 2 diabetes mellitus in Korea.

Methods: We used data from 3,596 individuals aged 45 years or older who participated in the vitamin test using the Korean National Health Examination and Nutrition Survey 2016?2018. The blood vitamin A and E concentrations equal to or above 0.70 and 20.0, which are upper normal limit, were classified as the fully sufficient group. An uncorrected analysis was conducted first, followed by adjustment for sex, age, income level, education level, marital status, BMI, hypertension, and dyslipidemia variables.

Results: For vitamin A, the difference in BMI, vitamin E, sex, high blood pressure, hyperlipidemia, and diabetes was significant, depending on whether it was the full adequate group or not. The full adequate group was significantly higher in BMI, vitamin E, males, high blood pressure, hyperlipidemia, and diabetes (BMI: 24.57 vs. 24.09, vitamin E: 16.81 vs. 14.04, hypertension: 42.0% vs. 32.7%, hyperlipidemia: 34.1% vs. 25.7%, diabetes: 20.9% vs. 15.2%). For vitamin E, differences in BMI, vitamin A, sex, and hyperlipidemia were significant, depending on whether a full adequate group was present. The full adequate group was significantly higher in BMI, vitamin A, females, and hyperlipidemia (BMI: 24.62 vs. 24.12, vitamin A: 0.65 vs. 0.54, hyperlipidemia: 34.5% vs. 26.3%). The probability of diabetes in the calibration model was significantly lower at 0.648 times than in non-vitamin E full estimate group cases (P<0.05).

Conclusion: We conclude that blood vitamin E levels and diabetes prevalence are correlated.

키워드

Vitamin E; Blood Vitamin E Level; Diabetes Mellitus; Republic of Korea

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