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Incidence, Risk Factors, and Prediction of Myocardial Infarction and Stroke in Farmers: A Korean Nationwide Population-based Study

Journal of Preventive Medicine and Public Health 2020년 53권 5호 p.313 ~ 322
이소람, 이헌주, 김혜심, 고상백,
소속 상세정보
이소람 ( Lee So-Lam ) - Yonsei University Wonju College of Medicine Department of Preventive Medicine
이헌주 ( Lee Hun-Ju ) - Yonsei University Wonju College of Medicine Department of Preventive Medicine
김혜심 ( Kim Hye-Sim ) - Yonsei University Wonju College of Medicine Center of Biomedical Data Science
고상백 ( Koh Sang-Baek ) - Yonsei University Wonju College of Medicine Department of Preventive Medicine

Abstract


Objectives: This study was conducted to determine the incidence and risk factors of myocardial infarction (MI) and stroke in farmers compared to the general population and to establish 5-year prediction models.

Method: The farmer cohort and the control cohort were generated using the customized database of the National Health Insurance Service of Korea database and the National Sample Cohort, respectively. The participants were followed from the day of the index general health examination until the events of MI, stroke, or death (up to 5 years).

Results: In total, 734 744 participants from the farmer cohort and 238 311 from the control cohort aged between 40 and 70 were included. The age-adjusted incidence of MI was 0.766 and 0.585 per 1000 person-years in the farmer and control cohorts, respectively. That of stroke was 0.559 and 0.321 per 1000 person-years in both cohorts, respectively. In farmers, the risk factors for MI included male sex, age, personal history of hypertension, diabetes, current smoking, creatinine, metabolic syndrome components (blood pressure, triglycerides, and high-density lipoprotein cholesterol). Those for stroke included male sex, age, personal history of hypertension, diabetes, current smoking, high γ-glutamyl transferase, and metabolic syndrome components (blood pressure, triglycerides, and high-density lipoprotein cholesterol). The prediction model showed an area under the receiver operating characteristic curve of 0.735 and 0.760 for MI and stroke, respectively, in the farmer cohort.

Conclusions: Farmers had a higher age-adjusted incidence of MI and stroke. They also showed distinct patterns in cardiovascular risk factors compared to the general population.

키워드

Myocardial infarction; Stroke; Cardiovascular diseases; Coronary artery diseases; Cerebrovascular diseases; Farmers

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