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Pituitary Pars Intermedia Dysfunction with Laminitis in a Horse

한국임상수의학회지 2021년 38권 1호 p.41 ~ 44
이은비, 천용우, 박경원, 강태영, 서종필,
소속 상세정보
이은비 ( Lee Eun-Bee ) - Jeju National University College of Veterinary Medicine
천용우 ( Chun Yong-Woo ) - J&C Equine Hospital
박경원 ( Park Kyung-Won ) - Jeju National University College of Veterinary Medicine
강태영 ( Kang Tae-Young ) - Jeju National University College of Veterinary Medicine
서종필 ( Seo Jong-Pil ) - Jeju National University College of Veterinary Medicine

Abstract


Pituitary pars intermedia dysfunction (PPID), often referred to as equine Cushing's disease, is a common endocrine disorder often diagnosed in older horses. A 13-year-old 460 kg Warmblood gelding showed clinical signs suggestive of PPID, including hypertrichosis, fat redistribution, polyuria and polydipsia (PU/PD), and weight loss. Physical examination, complete blood cell count, and serum chemistry results were normal. However, dexamethasone suppression and plasma adrenocorticotropic hormone (ACTH) level tests confirmed PPID. Three months after the confirmed diagnosis, the horse was referred again with symptoms of laminitis. Radiography and venography were performed to evaluate the laminitis severity level. However, the foot condition continued to worsen, and the horse was eventually euthanized. The purpose of this case report is to describe clinical signs and diagnosis of PPID with laminitis.

키워드

pituitary pars intermedia dysfunction; dexamethasone suppression test; laminitis; horse

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