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A Novel Strategy for the Microbial Removal of Heavy Metals: Cell-surface Display of Peptides

Biotechnology and Bioprocess Engineering 2021년 26권 1호 p.1 ~ 9
Wang Yuanyuan, Selvamani Vidhya, 유익건, 김태완, 홍순호,
소속 상세정보
 ( Wang Yuanyuan ) - University of Ulsan Department of Chemical Engineering
 ( Selvamani Vidhya ) - University of Ulsan Department of Chemical Engineering
유익건 ( Yoo Ik-Keun ) - University of Ulsan Department of Chemical Engineering
김태완 ( Kim Tae-Wan ) - Chonnam National University Department of Biotechnology and Bioengineering
홍순호 ( Hong Soon-Ho ) - University of Ulsan Department of Chemical Engineering

Abstract


Cell surface engineering is a rapidly developing technology of microorganism that achieves modification of cell surface function by joining external functional peptides with surface anchoring proteins, for example, Outer Member Protein (OMP). On account of these proteins possessing metal responsive motifs, they can be specifically used for metal adsorption and dissociation. To elucidate the problems caused by heavy metals and develop various technologies for their removel or recovery, various metal-binding proteins/peptides fused on microorganism cell surface have been applied as novel methods. During the past few years, bacterial cell surface display strategy has received growing attention for their availability to eliminate heavy metals. In this paper, the existing problems, progress, and suggestions for furture of the peptide displaying system are summarized.

키워드

wastewater treatment; biosorption; cell-surface display; bacteria; yeast; algae

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