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Comparison and Contrast of Bone and Dentin in Genetic Disorder, Morphology and Regeneration: A Review

Journal of Bone Metabolism 2021년 28권 1호 p.1 ~ 10
김재현, 이가영, 장우성, 기시형, 박주철,
소속 상세정보
김재현 ( Kim Jae-Hyun ) - Columbia University College of Dental Medicine
이가영 ( Lee Ga-Yeong ) - Columbia University College of Dental Medicine
장우성 ( Chang Woo-Sung ) - Columbia University College of Dental Medicine
기시형 ( Ki Si-Hyoung ) - Seoul National University School of Dentistry Department of Oral Histology-Developmental Biology
박주철 ( Park Joo-Cheol ) - Seoul National University School of Dentistry Department of Oral Histology-Developmental Biology

Abstract


The bone and dentin have distinct healing processes. The healing process of bones is regenerative, as newly formed tissues are morphologically and functionally similar to the original bone structures. In contrast, the healing process of dentin is reparative due to its failure to replicate some of its key morphological features. In this review, we compare and contrast the healing processes of bone and dentin. We describe how distinct morphological and physiological structures of the 2 tissues translate into different signaling molecules, growth factors, and matrix protein secretion.

키워드

Bone and bones; Bone regeneration; Dentin; Dentinogenesis; Regeneration

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