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Does Bone Mineral Density Differ between Fan-Beam and Pencil-Beam?: A Meta-Analysis and Systemic Review

Journal of Bone Metabolism 2021년 28권 1호 p.67 ~ 77
윤병호, 고영도, 유준일, 김수진, 이근영, 박성빈, 하용찬,
소속 상세정보
윤병호 ( Yoon Byung-Ho ) - Inje University College of Medicine Seoul Paik Hospital Department of Orthopaedic Surgery
고영도 ( Koh Young-Do ) - Ewha Womans University School of Medicine Ewha Womans University Mokdong Hospital Department of Orthopedic Surgery
유준일 ( Yoo Jun-Il ) - Gyeongsang National University School of Medicine Gyeongsang National University Hospital Department of Orthopaedic Surgery
김수진 ( Kim Su-Jin ) - Chung-Ang University College of Medicine Department of Radiology
이근영 ( Lee Guen-Young ) - Chung-Ang University College of Medicine Department of Radiology
박성빈 ( Park Sung-Bin ) - Chung-Ang University College of Medicine Department of Radiology
하용찬 ( Ha Yong-Chan ) - Chung-Ang University College of Medicine Department of Orthopaedic Surgery

Abstract


Background: Dual energy X-ray absorptiometry (DXA) has evolved from pencil-beam (PB) to narrow fan-beam (FB) densitometers. We performed a meta-analysis of the available observational studies to determine how different modes of DXA affect bone mineral density (BMD) measurements.

Methods: A total of 1,233 patients (808 women) from 14 cohort studies were included. We evaluated the differences in BMD according to the DXA mode: PB and FB. Additionally, we evaluated the differences in BMD between the 2 types of FB mode: FB (Prodigy) and the most recent FB (iDXA). Pairwise meta-analysis was performed, and weighted mean differences (WMD) were calculated for (total lumbar, total hip, and total body).

Results: No significant difference was observed in total lumbar (pooled WMD, ?0.013; P=0.152) and total hip BMD (pooled WMD, ?0.01; P=0.889), between PB and FB. However, total body BMD was significantly lower in the PB compared to the FB group (pooled WMD, ?0.014; P=0.024). No significant difference was observed in lumbar BMD (pooled WMD, ?0.006; P=0.567), total hip (pooled WMD, ?0.002; P=0.821), and total body (pooled WMD, 0.015; P=0.109), between Prodigy and iDXA.

Conclusions: The results of this study warrant the recommendation that correction equations should not be used when comparing BMD from different modes. Further research is still needed to highlight the ways in which differences between DXA systems can be minimized.

키워드

Absorptiometry; photon; Bone density; Densitometry; Osteoporosis

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