잠시만 기다려 주세요. 로딩중입니다.

Relationship between Lower Urinary Tract Dysfunction and Dementia

Dementia and Neurocognitive Disorders 2020년 19권 3호 p.77 ~ 85
나해리, 조성태,
소속 상세정보
나해리 ( Na Hae-Ri ) - Bobath Memorial Hospital Department of Neurology
조성태 ( Cho Sung-Tae ) - Hallym University Kangnam Sacred Heart Hospital Department of Urology

Abstract


Lower urinary tract dysfunction (LUTD) is a common health challenge in dementia patients with significant morbidity and socioeconomic burden. It often causes lower urinary tract (LUT) symptoms, restricts activities of daily life, and impairs quality of life. Among several LUT symptoms, urinary incontinence (UI) is the most prominent storage symptom in the later stages of dementia. UI in patients with dementia results not only from cognitive impairment, but also from urological defects such as detrusor overactivity. Management of LUTD in patients with dementia is based on multiple factors, including cognitive state, functional impairment, concurrent comorbidities, polypharmacy and urologic condition. Behavioral therapy under caregiver support represents appropriate treatment strategy for UI in these patients. Pharmacological treatment can be considered in patients refractory to behavioral therapy, but it is more effective when combined with behavioral therapy. Antimuscarinics and mirabegron, a beta-3 receptor agonist, are effective for managing storage symptoms involving the LUT. However, anticholinergic side effects in elderly subjects are a concern, particularly when there is a risk of exacerbating cognitive impairment with prolonged use of antimuscarinics. Proper recognition and treatment of LUTD in dementia can improve quality of life in these patients.

키워드

Urinary Bladder; Lower Urinary Tract Symptoms; Urinary Incontinence; Dementia; Overactive Urinary Bladder; Underactive Urinary Bladder

원문 및 링크아웃 정보

등재저널 정보

KCI
KoreaMed