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Platelet Inventory Management Program: Development and Practical Experience

Annals of Laboratory Medicine 2021년 41권 1호 p.95 ~ 100
이현지, 오승환, 조수연, 김인숙,
소속 상세정보
이현지 ( Lee Hyun-Ji ) - Pusan National University Yangsan Hospital Department of Laboratory Medicine
오승환 ( Oh Seung-Hwan ) - Pusan National University Yangsan Hospital Department of Laboratory Medicine
조수연 ( Jo Su-Yeon ) - Pusan National University Yangsan Hospital Department of Laboratory Medicine
김인숙 ( Kim In-Suk ) - Pusan National University Yangsan Hospital Department of Laboratory Medicine

Abstract


Background: Patients with ongoing or expected bleeding require platelet (PLT) transfusions; however, owing to the testing required after a blood donation, manufacturing PLT products may take 1.5?2.0 days after a request is made. This supply-demand mismatch leads clinicians to retain spare PLTs for transfusions, leading to increased PLT discard rates. We developed a PLT inventory management program to supply PLTs more efficiently to patients requiring PLT transfusions within the expiration date, while reducing PLT discard rates.

Methods: PLT concentrates (58,863 and 58,357 units) and apheresis products (7,905 and 8,441 units) were analyzed from May 2015 to November 2017 and from December 2017 to January 2020, respectively. We developed a program to manage total PLT inventories and prospective PLT transfusion patients based on blood type, blood product, and remaining period of efficacy; the program facilitates PLT preparation transfer to non-designated patients within the remaining period of efficacy.

Results: The overall PLT concentrate discard rate was 3,254 (2.78%): 1,811 (3.07%) units before and 1,443 units (2.41%) after program application (P<0.001). The discard rate owing to expiration was reduced from 69 units (3.81%) before to two units (0.14%) after program application (P<0.001).

Conclusions: This program can guide the allocation of PLT preparations based on the remaining period of efficacy, enabling PLT products to be used before their expiration date and reducing PLT product discard rate.

키워드

Platelet concentrates; Apheresis; Transfusions; Discard rate; Inventory program; Expiration date

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