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수면 연관 장애과 중추신경계 염증성 질환

Sleep Related Disorders and Inflammatory Diseases of the Central Nervous System

Journal of Sleep Medicine 2020년 17권 2호 p.108 ~ 112
현재원, 김수현, 김호진,
소속 상세정보
현재원 ( Hyun Jae-Won ) - National Cancer Center Research Institute and Hospital Department of Neurology
김수현 ( Kim Su-Hyun ) - National Cancer Center Research Institute and Hospital Department of Neurology
김호진 ( Kim Ho-Jin ) - National Cancer Center Research Institute and Hospital Department of Neurology

Abstract


Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory diseases of the central nervous system and inflammatory conditions involving sleep-related anatomical structures, associated with sleep-related disorders. After the identification of pathogenic anti-aquaporin-4 antibodies, NMOSD?previously considered a variant of MS?is now regarded as a distinct entity. A higher prevalence of sleep-related disorders is reported in individuals with MS compared to the general population, and recent evidence suggests the same is true in NMOSD. Timely recognition and multidisciplinary therapeutic approaches for sleep-related disorders in individuals with MS or NMOSD improve the patient’s quality of sleep and life. Therefore, this review aims to provide clinicians with a comprehensive understanding of the comorbid conditions and diagnostic and therapeutic strategies in clinical practice.

키워드

Sleep; Inflammation; Central nervous system

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