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사회적 시차가 젊은 폐쇄성 수면무호흡증 환자의 수면과 호흡 장애에 미치는 영향

Effect of Social Jetlag on Sleep and Respiratory Disturbance in Young Patients with Obstructive Sleep Apnea Syndrome

Journal of Sleep Medicine 2020년 17권 2호 p.181 ~ 187
조현진, 장은희, 최수정, 서수연, 주은연,
소속 상세정보
조현진 ( Jo Hyun-Jin ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Neurology
장은희 ( Jang Eun-Hee ) - Sungshin Women’s University Department of Psychology
최수정 ( Choi Su-Jung ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Neurology
서수연 ( Suh Soo-Yeon ) - Sungshin Women’s University Department of Psychology
주은연 ( Joo Eun-Yeon ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Neurology

Abstract


Objectives: Circadian misalignment may increase the risk of obesity and related obstructive sleep apnea (OSA). Considerable young adults have social jetlag (SJL), which is defined as the time discrepancy between workdays and free days. We aim to evaluate the relationship between SJL and sleep and respiratory disturbance in patients with untreated OSA patients.

Methods: A total of 180 OSA patients under the age of 50 [mean 38.3±8.0 y, 93.3% male, mean apnea-hypopnea index (AHI) 38.2±27.4 /h] were recruited from the university affiliated sleep clinic and fulfilled sleep-related questionnaires including Munich Chronotype Questionnaire (MCTQ). SJL was defined as the difference in sleep midpoints between work and free days. Patients were divided into three groups with SJL less than 1 hour, 1?2 hours, and 2 hours or more and the clinical and sleep data of each group were compared.

Results: 51.6% (n=93) suffered from significant SJL (≥1 h). Patients with ≥2h of SJL (16.6%, n=30) had the largest neck circumference (NC). AHI and sleep parameters were not significantly different among groups except lowest oxygen saturation (LoS) was the lowest in the group of ≥2 h. SJL was positively correlated with body mass index and NC and negatively correlated with LoS after adjusting for age and sex.

Conclusions: About a half of young adults with OSA have significant SJL more than 1 h. This study suggests that SJL is associated with being overweight, while it seems not increase the severity of OSA nor deteriorate sleep quality in young adults.

키워드

Obstructive sleep apnea; Circadian rhythm; Chronotype; Sleep; Obesity

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