잠시만 기다려 주세요. 로딩중입니다.

Surgical approach for the treatment of thymic carcinoma: 201 cases from a multi-institutional study

Precision and Future Medicine 2020년 4권 4호 p.149 ~ 160
Jeon Yeong-Jeong, 최용수, 조정호, 김홍관, 이근동, 김동관, 강창현, 김영태, 이창영, 이진구,
소속 상세정보
 ( Jeon Yeong-Jeong ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Thoracic and Cardiovascular Surgery
최용수 ( Choi Yong-Soo ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Thoracic and Cardiovascular Surgery
조정호 ( Cho Jong-Ho ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Thoracic and Cardiovascular Surgery
김홍관 ( Kim Hong-Kwan ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Thoracic and Cardiovascular Surgery
이근동 ( Lee Geun-Dong ) - University of Ulsan College of Medicine Asan Medical Center Department of Thoracic and Cardiovascular Surgery
김동관 ( Kim Dong-Kwan ) - University of Ulsan College of Medicine Asan Medical Center Department of Thoracic and Cardiovascular Surgery
강창현 ( Kang Chang-Hyun ) - Seoul National University College of Medicine Seoul National University Hospital Department of Thoracic and Cardiovascular Surgery
김영태 ( Kim Young-Tae ) - Seoul National University College of Medicine Seoul National University Hospital Department of Thoracic and Cardiovascular Surgery
이창영 ( Lee Chang-Young ) - Yonsei University College of Medicine Severance Hospital Department of Thoracic and Cardiovascular Surgery
이진구 ( Lee Jin-Gu ) - Yonsei University College of Medicine Severance Hospital Department of Thoracic and Cardiovascular Surgery

Abstract


Purpose: This study aimed to compare the outcomes of surgical approach (video-assisted thoracoscopic surgery [VATS] vs. sternotomy vs. thoracotomy) for the treatment ofthymic carcinoma

Methods: We retrospectively reviewed 201 patients with pathologically proven thymic carcinoma who underwent surgicalresection atfour Korean institutions.

Results: From 2007 to 2013, 158 sternotomy, 33 VATS and 10 thoracotomy were conducted forthymic carcinoma. Open group underwent more preoperative biopsy (41.8% and 50% vs. 15.2%, P=0.012) and neoadjuvant treatment (22.2% and 30% vs. 0%, P=0.008) than VATS group. In preoperative imaging, tumor size of VATS group was smaller than sternotomy group (3.8±1.1 cm vs. 5.8±2 cm, P<0.05) and 91% of the VATS group was clinicaltumor-node-metastasis (TNM) stage I. The lengths of chesttube and mechanical ventilation duration, postoperative hospital day and intensive care unit stay were shorterin VATS group than open group (P<0.001). The incidence of postoperative complications of VATS group was lower than sternotomy group (P=0.014). The 5-year overall survival of the sternotomy, VATS and thoracotomy group were 100%, 100% and 87.5%±11.7%, respectively (P=0.107). The 5-year recurrence-free survival rate was not significantly different between the groups (55.4%±4.5%, 67.9%±12.1%, and 87.5%±11.7%; P=0.131)

Conclusion: The VATS approach of surgical treatment for thymic carcinoma can be selectively employed in small (<5 cm) and TNM stage I tumor without compromise of oncologic outcome.

키워드

Thymus neoplasms; Carcinoma; Thoracic surgery, video-assisted

원문 및 링크아웃 정보

등재저널 정보