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Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study

Endocrinology and Metabolism 2021년 36권 1호 p.196 ~ 200
지원준, Lee Ru-Gyeom, 허경민, Kang Min-Sun, 황인철, Radnaabaatar Munkhzul, 이대호, 정재헌,
소속 상세정보
지원준 ( Ji Won-Jun ) - University of Ulsan College of Medicine Asan Medical Center Department of Pulmonary and Critical Care Medicine
 ( Lee Ru-Gyeom ) - Gachon University College of Medicine Gil Medical Center Artificial Intelligence and Big-Data Convergence Center
허경민 ( Huh Kyung-Min ) - Sungkyunkwan University School of Medicine Samsung Medical Center Department of Medicine
 ( Kang Min-Sun ) - Gachon University College of Medicine Gil Medical Center Artificial Intelligence and Big-Data Convergence Center
황인철 ( Hwang In-Cheol ) - Gachon University College of Medicine Gil Medical Center Department of Family Medicine
 ( Radnaabaatar Munkhzul ) - Gachon University College of Medicine Gil Medical Center Artificial Intelligence and Big-Data Convergence Center
이대호 ( Lee Dae-Ho ) - Gachon University College of Medicine Gil Medical Center Department of Internal Medicine
정재헌 ( Jung Jae-Hun ) - Gachon University College of Medicine Department of Preventive Medicine

Abstract


Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m2; adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m2; aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI ≥30 kg/m2) showed similar but non-significant trend. Females and those <50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19.

키워드

COVID-19; Obesity; Overweight; Infections

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