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Phylogenetic Analysis for the Origin of Typhoid Fever Outbreak on Jeju Island, Korea, in 2017

Infection & Chemotherapy 2020년 52권 3호 p.421 ~ 426
이근화, 유정래, 김영리, 허상택,
소속 상세정보
이근화 ( Lee Keun-Hwa ) - Hanyang University College of Medicine Department of Microbiology and Immunology
유정래 ( Yoo Jeong-Rae ) - Jeju National University School of Medicine Department of Internal Medicine
김영리 ( Kim Young-Ree ) - Jeju National University School of Medicine Department of Laboratory Medicine
허상택 ( Heo Sang-Taek ) - Jeju National University School of Medicine Department of Internal Medicine

Abstract


In June 2017, on Jeju Island, six patients were diagnosed with typhoid fever. All six patients were admitted to our hospital with fever, all of them had been working at the same hotel. The gyrA and gyrB genes of four out of six Salmonella typhi cases were amplified by polymerase chain reaction. The phylogenetic tree of the genes showed that the S. Typhi isolates from Jeju Island in 2017 had the same genotype and were similar to isolates from the United Kingdom. The origin of the isolates of the outbreak was the same, and the disease strain may have been imported from outside of Korea.

키워드

Phylogenetic analysis; Outbreak; Typhoid fever; Jeju Island; Korea

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