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인동(忍冬)의 기철(忌鐵) 및 반철(伴鐵) 추출시(抽出時) 추출물(抽出物)의 변화(變化)

Extract changes of Caulis Lonicerae Japonicae according to with or without Iron

대한한의학방제학회지 2020년 28권 3호 p.281 ~ 287
정덕자, 정대화, 장미희, 박정아, 김상찬,
소속 상세정보
정덕자 ( Jeong Deok-Ja ) - Daegu Haany University
정대화 ( Jung Dae-Hwa ) - D&B Bio
장미희 ( Jagn Mi-Hee ) - D&B Bio
박정아 ( Park Chung-A ) - Daegu Haany University
김상찬 ( Kim Sang-Chan ) - Daegu Haany University

Abstract


Objectives : In case of herbs decoction, the ceramic or earthware pots was recommended, but not the metals, particularly iron or aluminum, which could cause unknown chemical reactions. In Korean Medical classics, it has been known that some herbs including Caulis Lonicerae Japonicae (CL) were not recommended to boil with iron pot. This study investigates the physical changes of extracts of CL with or without iron.

Methods : CL was decocted with reflux cooling extraction system to prevent evaporation and volatilization. Content of polyphenol was detected by Folin-Denis method and the levels of loganin and chlorogenic acid were evaluated by UPLC.

Results : The color of extract with glass beads (GB) is yellowish brown, and the iron beads (IB) is blackish brown. Polyphenol and chlorogenic acid levels were reduced in IB extracts.

Conclusions : The color of extract was change to blackish brown, and polyphenol and chlorogenic acid levels were reduced in CL extract with iron. Therefore, iron pots is not suitable for CL extraction.

키워드

Caulis Lonicerae Japonicae; Decoction; Iron; Chlorogenic acid

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