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The Comparative Effect of Nopal and Mucilage in Metabolic Parameters in Rats with a High-Fructose Diet

Journal of Medicinal Food 2019년 22권 5호 p.538 ~ 541
Cardenas Yolitzy, Rios-Silva Monica, Huerta Miguel, Lopez Marisa, Bricio-Barrios Jaime, Ortiz-Mesina Monica, Urzua Zorayda, Saavedra-Molina Alfredo, Trujillo Xochitl,
소속 상세정보
 ( Cardenas Yolitzy ) - University of Colima University Center for Biomedical Research
 ( Rios-Silva Monica ) - University of Colima University Center for Biomedical Research
 ( Huerta Miguel ) - University of Colima University Center for Biomedical Research
 ( Lopez Marisa ) - University of Colima University Center for Biomedical Research
 ( Bricio-Barrios Jaime ) - University of Colima University Center for Biomedical Research
 ( Ortiz-Mesina Monica ) - Mexican Institute of Social Security
 ( Urzua Zorayda ) - Mexican Institute of Social Security
 ( Saavedra-Molina Alfredo ) - San Nicolas de Hidalgo Michoacan University Institute of Chemical-Biological Research
 ( Trujillo Xochitl ) - University of Colima University Center for Biomedical Research

Abstract


Nopal is used in Mexico as both food and traditional medicine for metabolic diseases. Our aim was to analyze the effect of the chronic administration of mucilage fiber extracted from nopal (Opuntia ficus indica; 500?mg/kg body weight per day) on male Wistar rats on a high-fructose diet (HFD). After which three groups were administered one of the following for 30 days: whole-fresh nopal mixed in water, mucilage, and control. Metabolic and hemodynamic parameters (triglycerides, cholesterol, fasting glucose, oral glucose tolerance test, blood pressure, and abdominal circumference) were determined. Rats administered nopal and mucilage had lower levels of triglycerides and diastolic arterial pressure than control, but only nopal had significant differences. Furthermore, systolic and diastolic pressure were higher in the control group. Thus, whole nopal and mucilage improve metabolic parameters in rats fed a HFD.

키워드

high-fructose diet; metabolic syndrome; mucilage; nopal

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