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Evaluation of the Safety of Daily Consumption of Kaempferia parviflora Extract (KPFORCE): A Randomized Double-Blind Placebo-Controlled Trial

Journal of Medicinal Food 2019년 22권 11호 p.1168 ~ 1174
Yoshino Susumu, Awa Riyo, 미야케 야스오, Fukuhara Ikuo, Sato Hisao, Endo Yoshiki, Tomita Shinpei, Kuwahara Hiroshige,
소속 상세정보
 ( Yoshino Susumu ) - Maruzen Pharmaceuticals Co. Ltd. Research Center
 ( Awa Riyo ) - Maruzen Pharmaceuticals Co. Ltd. Research Center
미야케 야스오 ( Miyake Yasuo ) - Maruzen Pharmaceuticals Co. Ltd. Research Center
 ( Fukuhara Ikuo ) - Fukuhara Clinic
 ( Sato Hisao ) - New Drug Research Center Inc.
 ( Endo Yoshiki ) - New Drug Research Center Inc.
 ( Tomita Shinpei ) - New Drug Research Center Inc.
 ( Kuwahara Hiroshige ) - Maruzen Pharmaceuticals Co. Ltd. Research Center

Abstract


This study's aim was to evaluate the safety of daily consumption of Kaempferia parviflora extract (KPE) using a randomized double-blind placebo-controlled study with 52 recruited healthy Japanese subjects. Each subject received five KPE tablets (containing 150?mg of KPFORCE™/tablet) or placebo daily for 4 weeks. There were no adverse events related to KPE intake or any abnormalities compared with placebo group in anthropometric, cardiovascular, blood, and urine parameters during the course of the study. Thus, daily KPE ingestion was found to be safe in healthy Japanese men and women.

키워드

healthy subjects; Japanese; randomized clinical trial; toxicity

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