잠시만 기다려 주세요. 로딩중입니다.

A Snack Formulated with Ingredients to Slow Carbohydrate Digestion and Absorption Reduces the Glycemic Response in Humans: A Randomized Controlled Trial

Journal of Medicinal Food 2020년 23권 1호 p.21 ~ 28
Rebello Candida J., Johnson William D., Pan Yang, Larrivee Sandra, Zhang Dachuan, Nisbet Mark, Johnson Jodee, Chu Yi Fang, Greenway Frank L.,
소속 상세정보
 ( Rebello Candida J. ) - Louisiana State University System Pennington Biomedical Research Center
 ( Johnson William D. ) - Louisiana State University System Pennington Biomedical Research Center
 ( Pan Yang ) - PepsiCo R&D
 ( Larrivee Sandra ) - Louisiana State University System Pennington Biomedical Research Center
 ( Zhang Dachuan ) - Louisiana State University System Pennington Biomedical Research Center
 ( Nisbet Mark ) - PepsiCo R&D
 ( Johnson Jodee ) - PepsiCo R&D
 ( Chu Yi Fang ) - PepsiCo R&D
 ( Greenway Frank L. ) - Louisiana State University System Pennington Biomedical Research Center

Abstract


This study compared the effect of a snack with ingredients to slow carbohydrate digestion (Test-snack) on postprandial blood glucose and insulin concentrations and subjective appetite ratings. We hypothesized that Test-snack would lower glucose and insulin responses and reduce appetite compared with a Control-snack. Overweight or obese subjects (n?=?17) completed a randomized crossover study. Glucose, insulin, and appetite ratings were measured before consuming each snack or white bread (Bread) and over a period of 4?h. Subjects received Test-snack, Control-snack, or Bread in random order at least a week apart. The a priori primary outcome was the glucose response, and the secondary outcomes were appetite ratings and insulin responses. Mixed effects statistical models were used to perform analysis of variance in terms of the area under curve (AUC) and at specific time points. The 2-h AUC for glucose was significantly lower with Test-snack compared to Control-snack and Bread (AUC and 95% confidence intervals: Test?=?2186.43 [1783.36?2589.51]; Control?=?3293.75 [2893.97?3693.54]; Bread?=?2800.28 [2405.79?3194.77] mg/dL · min). Four-hour AUC for glucose, and insulin, followed a similar pattern except that Test-snack did not differ from Bread. The glucose concentrations peaked at 45?min under all three conditions, but Test-snack elicited a lower response than Control-snack and Bread (P?

키워드

appetite; functional food; glucose; insulin; starch digestion

원문 및 링크아웃 정보

등재저널 정보