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Update on Current Technologies for Deep Brain Stimulation in Parkinson’s Disease

Journal of Movement Disorders 2020년 13권 3호 p.185 ~ 198
Paff Michelle, Loh Aaron, Sarica Can, Lozano Andres M., Fasano Alfonso,
소속 상세정보
 ( Paff Michelle ) - University of Toronto University Health Network Division of Neurosurgery
 ( Loh Aaron ) - University of Toronto University Health Network Division of Neurosurgery
 ( Sarica Can ) - University of Toronto University Health Network Division of Neurosurgery
 ( Lozano Andres M. ) - University of Toronto University Health Network Division of Neurosurgery
 ( Fasano Alfonso ) - Krembil Brain Institute

Abstract


Deep brain stimulation (DBS) is becoming increasingly central in the treatment of patients with Parkinson’s disease and other movement disorders. Recent developments in DBS lead and implantable pulse generator design provide increased flexibility for programming, potentially improving the therapeutic benefit of stimulation. Directional DBS leads may increase the therapeutic window of stimulation by providing a means of avoiding current spread to structures that might give rise to stimulation-related side effects. Similarly, control of current to individual contacts on a DBS lead allows for shaping of the electric field produced between multiple active contacts. The following review aims to describe the recent developments in DBS system technology and the features of each commercially available DBS system. The advantages of each system are reviewed, and general considerations for choosing the most appropriate system are discussed.

키워드

Deep brain stimulation; Parkinson disease; Surgery; Technology; Therapy

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