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Cryopreservation of mouse resources

Laboratory Animal Research 2020년 36권 1호 p.33 ~ 33
Takeo Toru, Nakao Satohiro, Nakagawa Yoshiko, Sztein Jorge M., Nakagata Naomi,
소속 상세정보
 ( Takeo Toru ) - Kumamoto University Institute of Resource Development and Analysis
 ( Nakao Satohiro ) - Kumamoto University Institute of Resource Development and Analysis
 ( Nakagawa Yoshiko ) - Kumamoto University Institute of Resource Development and Analysis
 ( Sztein Jorge M. ) - Kumamoto University Institute of Resource Development and Analysis
 ( Nakagata Naomi ) - Kumamoto University Institute of Resource Development and Analysis

Abstract


The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived in mouse banks worldwide. Researchers can request for the archived mouse strains for their research projects. The research infrastructure of mouse banks improves the availability of mouse resources, the productivity of research projects, and the reproducibility of animal experiments. Our research team manages the mouse bank at the Center for Animal Resources and Development in Kumamoto University and continuously develops new techniques in mouse reproductive technology to efficiently improve the system of mouse banking. In this review, we introduce the activities of mouse banks and the latest techniques used in mouse reproductive technology.

키워드

Genetically engineered mice; Mouse bank; Reproductive technology; Sperm; Embryo; Cryopreservation; In vitro fertilization; Cold storage; Hands-on workshop

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