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Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia

Journal of Neurogastroenterology and Motilitya 2021년 27권 2호 p.153 ~ 164
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Abstract


Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other frequently. The pathogenesis of IBS or FD is complicated and multi-factors related, in which infectious or non-infectious inflammation and local or systemic immune response play significant roles. There are few studies focusing on the mechanism of inflammation in patients with overlap syndrome of irritable bowel syndrome and functional dyspepsia (IBS-FD). This review focuses on current advances about the role of inflammation in the pathogenesis of IBS and FD and the possible mechanism of inflammation in IBS-FD.

키워드

Dyspepsia; Inflammation; Irritable bowel syndrome

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